Young-Choon Lee Selected Research

G(M3) Ganglioside

1/2018	Curcumin Downregulates Human GM3 Synthase (hST3Gal V) Gene Expression with Autophagy Induction in Human Colon Carcinoma HCT116 Cells.
8/2014	Ganglioside GM3 is required for caffeic acid phenethyl ester-induced megakaryocytic differentiation of human chronic myelogenous leukemia K562 cells.
1/2014	Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation.
1/2014	The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells.
1/2013	Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells.
5/2008	The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene.
7/2006	Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.

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Young-Choon Lee Research Topics

Disease

26	Neoplasms (Cancer) 01/2021 - 03/2003
9	Atherosclerosis 01/2021 - 05/2003
9	Hepatocellular Carcinoma (Hepatoma) 09/2014 - 07/2003
7	Neoplasm Metastasis (Metastasis) 09/2014 - 12/2002
6	Inflammation (Inflammations) 02/2020 - 01/2014
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2020 - 08/2008
5	Breast Neoplasms (Breast Cancer) 01/2017 - 12/2010
5	Neuroblastoma 08/2016 - 12/2003
4	Colonic Neoplasms (Colon Cancer) 01/2019 - 07/2006
4	Carcinoma (Carcinomatosis) 07/2018 - 05/2012
4	Melanoma (Melanoma, Malignant) 01/2013 - 11/2007
4	Arthritis (Polyarthritis) 03/2009 - 07/2003
4	Bone Resorption 08/2004 - 02/2002
3	Glioblastoma (Glioblastoma Multiforme) 02/2016 - 06/2006
3	Leukemia 06/2015 - 01/2004
3	Rheumatoid Arthritis 02/2008 - 07/2004
3	Carcinogenesis 02/2007 - 11/2004
3	Alzheimer Disease (Alzheimer's Disease) 07/2006 - 08/2003
3	Infections 12/2004 - 12/2002
3	Hepatitis B 07/2004 - 12/2002
2	Arteriosclerosis 01/2021 - 01/2019
2	Lung Neoplasms (Lung Cancer) 07/2018 - 01/2014
2	Adenocarcinoma of Lung 07/2018 - 01/2018
2	Liver Diseases (Liver Disease) 09/2014 - 05/2004
2	Osteosarcoma (Osteogenic Sarcoma) 12/2013 - 01/2013
2	Pathologic Neovascularization 02/2013 - 03/2009
2	Leiomyoma (Uterine Fibroids) 05/2008 - 06/2005
2	Disseminated Intravascular Coagulation 10/2005 - 03/2004
1	Virus Diseases (Viral Diseases) 01/2020
1	Atherosclerotic Plaque (Atheroma) 01/2019
1	Neuroinflammatory Diseases 10/2018

Drug/Important Bio-Agent (IBA)

10	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 03/2003
7	G(M3) GangliosideIBA 01/2018 - 07/2006
6	Proteins (Proteins, Gene)FDA Link 02/2020 - 07/2003
6	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2019 - 12/2002
4	AntioxidantsIBA 01/2021 - 05/2003
4	CaspasesIBA 01/2017 - 05/2012
3	Biological ProductsIBA 01/2021 - 04/2016
3	CytokinesIBA 01/2021 - 01/2014
3	Pharmaceutical PreparationsIBA 03/2019 - 05/2003
3	NF-kappa B (NF-kB)IBA 01/2019 - 11/2004
3	phorbolIBA 01/2019 - 03/2005
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2018 - 09/2005
3	haematoside synthetaseIBA 01/2018 - 01/2004
3	GlycosphingolipidsIBA 09/2017 - 08/2004
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2017 - 01/2017
3	SialyltransferasesIBA 01/2017 - 06/2006
3	cordycepinIBA 02/2016 - 04/2012
3	caffeic acid phenethyl esterIBA 08/2014 - 11/2004
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2014 - 03/2009
3	triptolideIBA 12/2013 - 12/2010
3	CollagenIBA 03/2007 - 07/2004
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2006 - 07/2003
3	Carthamus tinctorius Honghua extractIBA 10/2005 - 03/2004
3	silsosangamiIBA 08/2004 - 01/2004
2	LipopolysaccharidesIBA 02/2020 - 10/2018
2	Antineoplastic Agents (Antineoplastics)IBA 07/2019 - 01/2014
2	Anti-Bacterial Agents (Antibiotics)IBA 07/2019 - 04/2016
2	ascochlorinIBA 07/2019 - 04/2016
2	4-O-carboxymethylascochlorinIBA 01/2019 - 10/2018
2	CurcuminIBA 07/2018 - 01/2018
2	GD3 ganglioside (GD(3))IBA 01/2018 - 06/2004
2	Protein Glutamine gamma Glutamyltransferase 2IBA 09/2017 - 08/2008
2	Methanol (Carbinol)IBA 01/2017 - 12/2010
2	GangliosidesIBA 04/2016 - 08/2004
2	AntigensIBA 09/2014 - 05/2004
2	Small Interfering RNA (siRNA)IBA 09/2014 - 05/2008
2	GlycosyltransferasesIBA 09/2014 - 12/2004
2	hepatitis B virus X proteinIBA 09/2014 - 07/2004
2	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2014 - 02/2013
2	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2013 - 08/2004
2	Amyloid beta-PeptidesIBA 07/2006 - 12/2003
2	Fibrin Fibrinogen Degradation ProductsIBA 10/2005 - 03/2004
2	EndotoxinsIBA 10/2005 - 03/2004
2	CholesterolIBA 10/2005 - 05/2003
2	Fibrinogen (Factor I)FDA Link 10/2005 - 03/2004
2	formycin diphosphate (FDP)IBA 10/2005 - 03/2004
2	EnzymesIBA 12/2004 - 11/2004
2	Matrix Metalloproteinase 2 (Gelatinase A)IBA 10/2004 - 09/2004
2	GelatinIBA 09/2004 - 03/2003
2	Cathepsin KIBA 08/2004 - 11/2003
2	Glutamic Acid (Glutamate)FDA Link 12/2003 - 05/2003
2	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 08/2002 - 02/2002
1	Anti-Allergic Agents (Antiallergic Agents)IBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	avenanthramide-2CIBA 01/2021
1	3'-sialyllactoseIBA 01/2020
1	Sialic Acid Binding Ig-like Lectin 3IBA 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2020
1	OligosaccharidesIBA 01/2020
1	Toll-Like Receptor 4IBA 01/2019
1	esculentoside HIBA 01/2019
1	AcidsIBA 09/2017
1	Butanols (Butyl Alcohols)IBA 01/2017
1	Tetradecanoylphorbol AcetateIBA 01/2017
1	Cell Adhesion MoleculesIBA 01/2017
1	ascofuranoneIBA 01/2017

Therapy/Procedure

5	Therapeutics 06/2015 - 02/2004
2	Oral Administration 11/2004 - 08/2003
1	Traditional Medicine (Folk Remedies) 01/2017